Spatial Genomics Scientist
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In Roche’sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio.
Operating as an integrated ecosystem, the 360 Lab environment will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing and learning experiences in close collaboration with our therapeutic areas and functions. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities.
We are currently recruiting scientific professionals with varied backgrounds in Flow Cytometry, Genomics, Proteomics, Histopathology and Microscopy / Imaging. In these new roles, your collaborative mindset is as valued as your scientific expertise. The 360 Labs are by nature a hands-on, interactive workplace where face to face presence in our labs is a priority. Our ambition is to bring to life a thriving workplace environment, acting as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability.
Job Mission and Impact
The Genomics Core Technology Platform within the 360 Labs Initiative is seeking to expand its team with an experienced, highly motivated, collaborative, and customer-centric Spatial Genomics Scientist specializing in advanced spatial transcriptomics methods and their application to early drug discovery projects. The ideal candidate will have a strong background in the life sciences and brings cutting-edge expertise in one or various approaches, such as 10x Visium (HD) and Xenium, MERFISH, Slide-seq, Stereo-Seq, CosMX, and GeoMX, generating spatial gene expression data. You will work with urgency as part of a matrix team, collaborating with experts across various therapeutic disease areas and functions to provide spatial transcriptomics insights into early drug discovery efforts and will contribute to the ongoing development of the Genomics Core Technology Platform within the pRED organization.
Your Role and Responsibilities
You will be accountable for the planning, design, and execution of spatial transcriptomics workflows, with a focus on implementing and optimizing both routine and custom spatially-resolved transcriptomics techniques;
You will ensure the continued production of high-quality research data by performing regular quality control and troubleshooting of spatial transcriptomics experiments and related instrumentation;
You will embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies/approaches in the spatial transcriptomics field.
Your Profile
You hold either a MS or a PhD degree in biology, biochemistry, or a related field, with 6-8 years or 2-4 years of professional experience, respectively, focused on spatial transcriptomics, either in an academic setting or within a core genomics-focused group in the pharmaceutical and/or biotechnology industry;
You have significant practical, hands-on experience in implementing, optimizing, and executing both routine and custom-designed assays with spatial transcriptomics devices, such as the 10x Genomics Visium, Xenium or similar, in a rigorous and reproducible manner;
You have a proven ability to collaborate within and across matrix teams, including molecular biologists, research histopathologists, and bioinformaticians, to design spatial transcriptomics experiments and interpret results.
In addition to your professional expertise and critical technical skills we are looking for candidates who:
Are resourceful and flexible in problem solving, have excellent organizational skills, and are able to work in a matrix environment with a sense of urgency in a fair, open and collaborative manner, ensuring that everyone has the required information at all times;
Can think outside the box and work in diverse, multicultural, global teams, with a demonstrated ability to implement new ideas in fast-paced research environments
Bring excellent written communication and presentation skills with a high fluency in English.
These positions are based in Basel.
Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo.Roche embraces diversity and equal opportunityin a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.