Senior Scientist, Cryo-Electron Microscope (Cryo-EM)
Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Cryo-electron microscope (Cryo-EM), located in Spring House, PA.
At Johnson & Johnson,?we believe health is everything. Our strength in healthcare innovation empowers us to build a?world where complex diseases are prevented, treated, and cured,?where treatments are smarter and less invasive, and?solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
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At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com/ for more information.
The Discovery Technologies and Molecular Pharmacology group is a dynamic, diverse and critical part of the Discovery Sciences organization in Janssen R&D. We are committed to the discovery and characterization of high-quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Areas. This mission requires deep scientific expertise across broad disciplines including chemistry, cellular and molecular pharmacology, enzymology, screening, protein science, and structural biology coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding and motivated individual to join our team as a Senior Scientist, Cryo-EM.
The Senior Scientist will:
- Be an active member of drug discovery teams, working closely with computational and medicinal chemists on structure-based drug design approaches for small/large molecule optimization.
- Be responsible for end-to-end structure determination via Cryo-EM and communicating these results to the project teams.
- Collaborate closely with protein scientists, biophysicists, protein NMR, and X-ray crystallography scientists as part of an integrated structural biology effort.
- Actively seek innovative strategies to handle complex targets including optimizing samples for single-particle cryo-EM and electron tomography (ET), grid preparation, data collection, processing, and analysis.
- Contribute to increasing the structural biology scientific expertise of the group by publishing high-impact research papers, attending and presenting at scientific conferences, internalizing impactful outside technologies and techniques, and establishing academic collaborations.
·Mentor lab scientists and contribute to the strategic planning of the Structural Biology group