Scientist in Microscopy Image Analysis & Data workflows in Lead Discovery (m/f/d)

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes usRoche.

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

This position is located in Lead Discovery, a department within Small Molecule Research which is part of the Therapeutic Modalities function, where the discovery of chemical starting points for further optimization in medicinal chemistry is our primary focus.

As a drug discovery research team, we continuously drive for excellence to uncover new chemical starting points addressing unmet medical needs. Here, we are offering an outstanding opportunity for a new team member with a passion for microscopy image analysis and data science.

• You are a microscopy image analysis expert and impact the discovery of new chemical starting points in lead identification and optimization programs. You have a critical role in advancing our understanding of drug targets and mechanisms of action in targeted and phenotypic screening approaches.

• You utilize your expertise to design, implement and execute image and data analysis strategies at scale for high-content imaging using cellular models (2D, 3D, organoids) by both segmentation / feature extraction and machine learning-based processes, data condensation and data visualization.

• You implement cutting-edge image analysis frameworks and QC standards to uncover complex patterns and extract relevant information from high-content imaging and screening datasets while closely working together with colleagues from the Assay Development and High Throughput Screening & Profiling teams.

• You own the business process and solution for new data workflows around high-content screening and act as the key connector between the research teams in Lead Discovery and colleagues from the pRED Data & Analytics department.

• You are a pivotal expert within our multidisciplinary matrix teams and as an individual contributor collaborating across pRED, internal stakeholders and external vendors.

• We are looking for a new team member with a track record in microscopy image analysis and a solid understanding of cellular biology and drug discovery principles. Experience in omics data analysis is beneficial, but not essential.

• You apply data science methodologies and techniques to analyze, interpret and interrogate large-scale data sets and create a F.A.I.R. data orchestration layer.

• You bring strong programming skills in languages such as Python, R or others, experience with relevant image analysis software tools such as CellProfiler, Imagence, ImageJ, FiJI or others as well as hands-on experience with popular deep learning frameworks (e.g. PyTorch, TensorFlow, Keras, Transformers).

• You communicate in a clear and concise manner and are able to manage stakeholders efficiently in a matrix team including technical and non-technical stakeholders.

• You thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development.

The scientific title of this position might be adjusted depending on the experience and seniority of the final candidate.

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.