Postdoctoral Research Position in Molecular Genetics of Sleep Disorders
UNIL is a leading international teaching and research institution, with over 5,000 employees and
17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL
encourages excellence, individual recognition and responsibility.
The laboratory of Dr. Anne Vassalli at the Department of Biomedical Sciences at the University of
Lausanne is seeking a highly motivated Postdoctoral Associate to lead an exciting research project
funded by the Swiss Federal Innovation Agency “Innosuisse”.
Our laboratory is interested in understanding the cause of the sleep disorder narcolepsy. Following
our recent discovery of epigenetic silencing of the hypocretin/orexin gene in narcolepsy patients,
the aim of the project is to provide Proof-of-Concept of the disease reversal by epigenetic drugs.
We seek to leverage diverse in vitro (cell-based) and in vivo (mouse model) approaches to identify
novel compounds (small molecules) that will reactivate the hypocretin/orexin gene and lead to the
development of the first disease-modifying treatment for narcolepsy.
Expected Start date: 01.11.2024
Contract length: 1 year renewable
Activity rate: 100%
Workplace: University of Lausanne - Bugnon/CHUV
• Plan, direct, and conduct advanced research experiments involving molecular biology and both cellular and mouse model systems.
• Evaluate and statistically analyze data
•Summarize research findings and publish results.
• Work closely with the principal investigator to design and dynamically optimize experimental strategies and directions of the project.
• Ph.D. in Life Science involving molecular/cellular neuroscience or neurogenetics.
• Experience in molecular biology, cell culture, molecular genetics, in vitro and in vivo
neuropharmacology.
• You are a dynamic, dedicated scientist, critical thinker, with a team player spirit. You are keen
to develop novel multidisciplinary skills to understand the basic mechanisms of neurological
diseases.
We offer a nice working place in a multicultural, diverse and dynamic academic environment. Opportunities for professional training, a lot of activities and other benefits to discover.
Dr Anne Vassalli
Write an email
Phone: 0041 21 692 5540 or 0041 79 669 5619
Deadline: 30.09.2024
Please send your CV, motivation letter and 2 recommendation letters in Word or PDF, preferably
as a single document titled with your name.
Only applications though this website will be considered.
We thank you for your understanding.
UNIL is committed to equal opportunities and diversity.
www.unil.ch/egalite
UNIL supports early career researchers.
www.unil.ch/graduatecampus
1015 Lausanne / Lausanne / CH-1015 Lausanne / Epalinges
