Postdoctoral Position in Tumor Immunology

Institution: University of Bern, Institute of Tissue Medicine and Pathology
Department: Experimental Pathology, Group Schenk (IP5)
Location: Murtenstrasse 31, 3008 Bern, Switzerland
Principal Investigator: Prof. Dr. Mirjam Schenk
Duration: 24 months, with potential extension to 48 months
Start Date: open now, latest start January 2025
Application Deadline: 31.08.2024
Contact Information:

• Email: Write an email
• Phone: +41 (0)75 430 99 97

  The Institute of Tissue Medicine and Pathology at the University of Bern is seeking a highly motivated and self-disciplined postdoctoral researcher to join the team of Prof. M. Schenk. The successful can-didate will work on a cutting-edge project focused on the comprehensive analysis of the tumor micro-environment in pancreatic ductal adenocarcinoma (PDAC). This research aims to discover novel bi-omarkers and identify therapeutic targets to improve the diagnosis and treatment of PDAC.

PDAC is an aggressive cancer with a poor prognosis and limited treatment options. This project aims to unravel the complexities of the tumor immune microenvironment using advanced imaging mass cytometry (IMC) and transcriptomic techniques (scRNA-seq and spatial transcriptomics). The integra-tion of these data with clinical parameters will facilitate the identification of key immune markers and therapeutic targets.Key Responsibilities

• Conduct high-dimensional immunophenotyping of PDAC tissues using IMC.
• Perform transcriptomic analyses including scRNA-seq and spatial transcriptomics.
• Analyze the relationships between the immune microenvironment, tumor mutational burden, and clinical outcomes.
• Design and perform in vivo experiments using murine models to assess the efficacy and mechanisms of novel treatments.
• Supervise and mentor graduate and undergraduate students in the lab.
• Assist in writing grant proposals and securing research funding.
• Collaborate with a multidisciplinary team of researchers, clinicians, and bioinformaticians.
• Prepare and present research findings at scientific conferences and in peer-reviewed journals.
  Qualifications
• PhD in a relevant field (e.g., Cancer Biology, Immunology).
• Strong background in tumor immunology and/or cancer research.
• Experience with high-dimensional data analysis, including transcriptomics and/or imaging mass cytometry.
• Proficiency in bioinformatics and statistical analysis tools (e.g., R, Python).
• Highly motivated and self-disciplined with excellent written and verbal communication skills in English.
• Ability to work independently and as part of a collaborative team.

Preferred Qualifications:

• Experience with immunology and cancer research.
• Knowledge of immunotherapy and its application in cancer treatment.
• Familiarity with clinical data integration and high-dimensional data analysis.
  Benefits
• Competitive salary and benefits package.
• Access to state-of-the-art research facilities and resources.
  o Opportunity to work in a dynamic and collaborative research environment.
  o Professional development opportunities and support for career advancement.
  Application Instructions
  Interested candidates should submit the following documents:
  o A cover letter detailing research interests and relevant experience.
  o Curriculum vitae (CV) including a list of publications.
  o Contact information for three professional references.
  o A brief statement of research goals (1-2 pages).

Please send the application materials as a single PDF file to Prof. Dr. Mirjam Schenk at Write an email by August 31, 2024.

Equal Opportunity Employer:

The University of Bern is committed to promoting diversity and inclusion in its workforce. We wel-come applications from all qualified individuals, regardless of race, gender, disability, or other char-acteristics.
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We look forward to receiving your application and exploring the potential for you to join our innova-tive research team at the University of Bern, Institute of Tissue Medicine and Pathology.

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