PhD student in Structural Biology by NMR 100%
PhD student in Structural Biology by NMR 100%
How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
A PhD student position funded by the Swiss National Science Foundation (SNSF) is available in the newly founded group of project leader Dr. Fengjie Wu, who is a recent Ambizione awardee hosted by Prof. Sebastian Hiller.
A PhD student position funded by the Swiss National Science Foundation (SNSF) is available in the newly founded group of project leader Dr. Fengjie Wu, who is a recent Ambizione awardee hosted by Prof. Sebastian Hiller.
Your position
The project studies the fundamental mechanism of G protein-coupled receptors (GPCRs) signaling by applying and developing unique cutting-edge NMR technology. Further biophysical methods (cryo-EM, ITC) are integrated in the workflow. A key part of this project will be the development of novel paramagnetic NMR methods and effective isotope labeling methods.
The research will dive into the atomic level to investigate the conformational dynamics of GPCRs. Such in-depth information will explain the functions of natural ligands or synthetic drugs in GPCR signaling and pharmacology. Based on the functional understanding, opportunities for new drug design will emerge.
The research will dive into the atomic level to investigate the conformational dynamics of GPCRs. Such in-depth information will explain the functions of natural ligands or synthetic drugs in GPCR signaling and pharmacology. Based on the functional understanding, opportunities for new drug design will emerge.
Your profile
- Master degree in biochemistry, chemistry, biophysics or a related scientific discipline at the time of the PhD start.
- Experience in one or several of the following areas: biomolecular NMR, GPCR, membrane protein biochemistry/biophysics, molecular biology, structural biology.
- Good communication skills in English.
- High motivation for challenges at the forefront of international research.
We offer you
- The Biozentrum of University Basel houses a large array of high-resolution NMR spectrometers (600, 700, 800, 900 MHz), a biophysics technology platform and a protein expression lab.
- The Wu group is part of the research cluster "Structural Biology and Biophysics" at the Biozentrum, which offers a stimulating interdisciplinary environment and in-house availability of all methods of modern structural biology.
- The student will benefit also from the embedding in the Hiller group, a dynamic and collaborative group of scientists with broad expertise.
- The PhD training will include structural biology, biophysics, biochemistry as well as formal education within the Biozentrum's graduate teaching program.
- Basel is an international city with people from 150 nations. Located where three countries meet - Switzerland, Germany and France - it is Europe's most important life sciences hub. Basel provides a high standard of living and a rich cultural atmosphere.
Application / Contact
Please apply online:
https://biped.biozentrum.unibas.ch/apply/phd-student-position_wugroup
Applications should include a cover letter, CV, BSc/MSc degree confirmation with detailed grades, and contact information of two reference persons.
Review of applications will start immediately and continue until the position is filled. Please note that only online applications via the application portal will be accepted.
Informal queries about the lab and research projects should be directed by email to Write an email
Please apply online:
https://biped.biozentrum.unibas.ch/apply/phd-student-position_wugroup
Applications should include a cover letter, CV, BSc/MSc degree confirmation with detailed grades, and contact information of two reference persons.
Review of applications will start immediately and continue until the position is filled. Please note that only online applications via the application portal will be accepted.
Informal queries about the lab and research projects should be directed by email to Write an email
Universität Basel
4000 Basel
4000 Basel
Lieu de travail
4000 Basel
À propos de l'entreprise
