Senior Genomic Biomarker Scientist

Conditions of Employment: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship)

So, if you think you are a strong fit for this position, please apply today!

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Excellent salary and benefits package offered.

About the job

We are seeking highly motivated candidates to join our R&D team in Lausanne and contribute to the development and application of advanced technologies in RNA-based therapeutics and diagnostics.

HAYA seeks candidates who are creative, scientifically bold, independent, goal-oriented, excellent communicators, motivated to learn new skills and work collaboratively in a fast-paced entrepreneurial environment.

Senior Genomic Biomarker Scientist

As an experienced and engaged Senior Genomic Biomarker Scientist, you will work in close collaboration with computational biology and pre-clinical R&D teams. You will apply your scientific acumen and creativity to build ViewHAYATM, a top-notch platform for biomarker discovery and validation. You will drive this platform forward to identify and develop CDx for HAYA’s therapeutic assets. You will provide matrix leadership and inspire others with your creative ideas as well as your technological and domain insights.

Responsibilities will include, but are not limited to, the following:

• Build and lead a small team of ~2-3 scientists to drive novel diagnostic and prognostic RNA biomarker discovery studies.
• Design, conceptualize and develop experimental and analytical procedures.
• Lead the strategy, development, validation and implementation of genetics and genomics-based biomarker assays.
• Be a subject expert in order to evaluate and apply genetics and genomics technologies and assays to ensure we gain relevant insights from precious sample materials.
• Manage all aspects of out-sourced (CROs) work packages.
• Actively participate in internal and external scientific meetings through presentations and critical evaluation of both internal results and emerging scientific literature.
• Inspire your team members and other scientists and train them in the application of new technologies.

Qualifications:

• PhD in molecular and/or RNA biology or related discipline with at least 5 years of experience in biomarker research.
• Strong expertise in genetics and genomics biomarker assays development.
• Deep technical expertise in molecular biology (PCR technologies) and next generation sequencing applications across platforms in various matrices (e.g. tissue, blood, body fluids, cells).
• Strong knowledge with tools, and resources used for the analysis and interpretation of genomic data.
• Proven excellence in building and managing scientific teams and completing challenging projects.
• Excellent organization skills and familiarity with a fast-paced work environment.
• Collaborative spirit and ability to thrive in a matrixed environment.
• Proven track record of handling multiple high priority tasks in parallel with internal and external collaborators.
• Excellent written and verbal communication skills.

Core Values:

• Creativity & Innovation. Scientifically curious and bold. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation. Able to challenge convictions and dogma.
• Teamwork. Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions.
• Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity. Self-starter mentality.
• Fast-acting/efficient. Proactive and quick decision making with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key tasks and priorities. Demonstrates tenacity and willingness to go the distance to get something done.
• Integrity. Does not cut corners. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Earns trust and maintains confidences. Expects a high level of personal performance and team performance. Follows-through on commitments.
• Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and to independently pursue and achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw key conclusions.

HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), - the ‘dark genomes’ information processing features and ‘source code’.

HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers.

Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.