Scientist – Isotope Synthesis, pCMC
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A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
That’s what makes us Roche.
In Roche’sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
This position is located in preclinical Chemistry, Manufacturing, and Controls (pCMC), a department within the Synthetic Molecule Research organization in Therapeutic Modalities. We pave the path to bring drug candidates from early research into development in a diverse, ambitious, and innovative environment. We collaborate actively with our discovery and development partners; functions providing cutting-edge technologies and scientific excellence to transform molecules into future medicines.
We are CMC experts and build our strength on a broad diversity of technical expertise in chemistry, formulation design, material science, and analytical chemistry, delivering and innovating in the space of small molecules, peptides, and nucleic acid based medicines.
We are offering an outstanding opportunity as a Scientist in Isotope Synthesis. In this role, you will be part of a team of radiolabeling experts and chemists, supporting a diverse portfolio of small molecule, peptides and nucleic acid discovery projects.
Your Impact:
You develop synthetic routes suitable for the supply of radiolabeled compounds required for pre-clinical and human studies. You are accountable for the scientific, technical excellence, and compliance of the work performed within your area of responsibility.
You stay abreast of developments and trends pertinent to small molecules, peptides, nucleic acids and large molecule radiolabeling. You attend relevant conferences, build strong internal and external relationships to maintain a strategic understanding of the drug R&D technology environment and recommend priorities.
You are committed to performing lab work.
We are seeking a committed individual who brings:
PhD in organic chemistry or Master degree with relevant professional experience with a focus on process chemistry or radiochemistry. You possess a sound understanding of the drug development process and a good knowledge of key aspects and scientific methods used to synthesize new drug candidates.
Deep knowledge of organic chemistry with excellent experimental skills, in particular in the synthesis, isolation, purification, and analytical characterization of drug substances.
Hands-on expertise in radiolabeling and stable isotope labeling chemistry with specific working knowledge of facilities and equipment and training in radiation protection is an advantage.
Expertise in working in a GMP environment, constantly improving best practices, is a plus.
Strong cross-functional teaming skills: you have an inclusive and collaborative way of interacting. You demonstrate good communication skills that enable you to effectively collaborate within cross-functional teams
Roche commits to recognising talent and aptitude. We prioritise encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.