RiSM internship in Solid State Science for Students in chemistry, chemical or process engineering, pharmacy, pharmaceutical sciences, pharmaceutical technology, or physics

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As part of the global technical development organization, the Particle Design group is the center of excellence for the design of drug substance particles with tailor-made solid-state properties to facilitate downstream processing to the drug product. This includes the development and optimization of the processes on laboratory scale, as well as scale-up of the corresponding manufacturing processes in close collaboration with the production sites. Our responsibilities also include the evaluation and implementation of new strategies to obtain particles with the desired properties.

As an Intern in the particle design group you will be working on one of the following project-areas:

Project A. Computational Intern Solid State Sciences

This project is intended to further evolve existing software solutions in the realms of solubility prediction, morphology prediction and crystal structure prediction. The project goal includes conducting literature research on new approaches and testing of these in small subprojects.

The (experimental) work is going to focus on: no experimental work expected.

Project B.Industrialization of Spherical Agglomeration/Crystallization Spherical crystallization

This project addresses two main challenges for the development of spherical agglomeration/crystallization processes:

1. Solvent selection: An efficient solvent selection is a crucial step in applying the technology to a new compound.

2. Endpoint determination for bridging liquid addition: Dosage endpoint detection during spherical agglomeration is important for scale-up, as the primary particles may undergo a certain variation heavily impacting the amount of bridging liquid needed to get the desired agglomerate quality.

You are a student (or you graduated within 12 months prior the start date) in the subject of chemistry, chemical or process engineering, pharmacy, pharmaceutical sciences, pharmaceutical technology, physics or a related field (preferably with a bachelor's degree) and have an interest and experience in crystallization and solid-state characterization. Furthermore, you are interested in using and sharing your knowledge as part of your internship in a modern working environment.

The (experimental) work is going to focus on: Screening procedure optimization for solvent system selection and spherical agglomeration experiments.

Your further profile for one of the positions:

• General:

  • Team-oriented and decision-making personality

  • Problem solving-oriented work habits

  • Good knowledge of MS-Office (Word, Excel, PowerPoint)

  • Proficient in English, German is a plus

  • Experience working in a lab-environment.

• For project area A: Basic knowledge of crystallization techniques. Basic knowledge of programming (e.g. Perl, Python) and an interest in computational chemistry.

• For project area B: Hands-on experience in various crystallization techniques, formation of emulsions and their stabilization, as well as crystallization techniques.

• For project area C: Basic knowledge of pressure driven filtration technologies, ideally in the area of cross-flow membrane filtration.

• For project area D: Knowledge in process engineering, powder processing, as well as powder characterization techniques

• For project area A: Basic knowledge of crystallization techniques. Basic knowledge of programming (e.g. Perl, Python) and an interest in computational chemistry.

This internship opportunity is one of a number of positions we offer in the department per semester. The interviews will take place on an interview day with all considered candidates and the whole department.

Your complete application includes the following documents

? A Current CV and a Motivation Letter

? A certificate of enrollment (if you are currently studying). If you want to use this

opportunity to do a Master’s or Diploma thesis, please highlight this in your application

? For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by

your university stating that an Internship is mandatory for your studies

Application deadline is 21.08.2024.

As part of your application, we would like you to complete a task. You can find the task description here:

Sustainability is an important aspect for our planet and the people living on it. In order to transform our world to a better one, the United Nations have published 17 Sustainable Development Goals (https://sdgs.un.org/goals).
Assume that you are writing your own grant application for a 12 months internship on the topic sustainability. Select at least one of the 17 goals, relate it to your education/study and propose a project topic for an internship out of it.
We are looking forward to receiving your proposal (max. 3 slides, pdf) together with your application.

During your application, please make sure to upload the following documents:

- Your up-to-date CV

- A certificate of enrollment (if you are currently studying)
- Your cover letter
- Your solution proposal for the task described above (max. 3 slides, pdf)

Please ensure that you have attached all the required documents before you submit your application in the system, as it will not be possible to attach any missing documents later.

For Non-EU/EFTA citizens:Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies

Selected candidates will be invited to a virtual interview day which will take place on 16.10.2024.

The Internship will start in 2025 for 9-12 months, please indicate your preferred start date and duration in your application.

More information about the Roche Internship program in Synthetic Molecules (RiSM) and other opportunities within this program you can findhere.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities

If you still have questions, then please check our FAQs and videos onhttps://careers.roche.com/global/en/faq

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