Research Associate in Neuroscience
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.
Research Associate in Neuroscience
In Roche’s Pharmaceutical Research and Early Development organization (pRED) we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
We are looking for a highly motivated research associate to join the Systems Neuroscience Section in the Neuroscience and Rare Disease (NRD) Research Department. The overarching goal of the Systems Neuroscience Section is to move forward drug discovery projects, from target assessment to early clinical phase, in the therapeutic area of neurodegenerative diseases.
The Opportunity
We are looking for an individual with high interest and determination to improve the lives of patients suffering from devastating neurodegenerative disorders. You will contribute to the identification and optimization of drug candidates from different modalities (small and large molecules, gene therapy, etc) by assessing their potential in disease models (in vitro and in vivo) and characterizing their mode of actions. You will be involved in research to find new targets and proof-of-concept studies to validate novel targets. You will be part of a new research lab and have the full opportunity to work in close collaboration with multidisciplinary experts to reach all together our goal to provide patients with innovative, safe and life changing treatments.
Your impact
Developing and optimizing assays to model disease-related pathological mechanisms using molecular biology, biochemical, biophysical and multi-omics approach
Developing cell culture and pluripotent stem cell models of human neurological disorders and implement electrophysiological readouts
Supporting characterization of in vivo models of disease
Leading and coordinating experimental processes in collaboration across the organization and with external partners
Analyzing, documenting and presenting the data to the lab and project teams
Consulting literature, proposing assay optimization and independently developing assays and implementing technologies for the success of portfolio projects
Working closely with members of the group, sharing duties in lab organization, maintaining a clean work environment, and actively contributing to the positive and collaborative work atmosphere within the group and beyond in the matrix structure of our drug discovery and research organization
Who you are
You are someone who wants to influence your own development. You enjoy teamwork, diligence and efficiency. You show initiative, organize multiple tasks effectively and take pride in delivering results of high quality. You are looking for a company where you receive the opportunity to pursue your interests across functions and geographies. Working in a multicultural environment motivates you.
Must have:
MSc/BSc in Life Sciences (cellular/ molecular biology, biochemistry, neuroscience, pharmaceutical sciences), or completion of an apprenticeship for a biology research associate (“Lehrabschluss”) with =2 years experience (PhD holders won’t be considered for this position)
Proficient in biochemical and biophysical assays, cell culture and sterile working techniques
Hands-on experience with iPSC-derived cells such as neurons and/or microglia
Experience in biochemical and immunoassays such as protein and RNA extraction, Western blot, ELISA, immunoprecipitation, immunocyto & histochemistry and gene expression analysis by RT-PCR
Rodent brain tissue sectioning (vibrotome sectioning) and imaging with confocal microscope
Experience with imaging on high-content instruments is advantageous
Digitally savvy with a strong sense and proficiency in generating FAIR data
Strong willingness to continuously learn and grow in your capabilities
Skillfully able to interact effectively with people, strong commitment to teamwork with a flexible mindset to an agile and highly collaborative environment with fast-paced project work.
You can communicate, write and present fluently in English
Excellent data management and record-keeping skills
Desirable:
Experience with basic animal handling and dissections & LTK1 certification or equivalent
Experience with multiplex or high-end omics instruments is a plus
Experience in automated image analysis with simple programming skills and an understanding of statistical concepts
Experienced in biosafety and general safety, health and environment lab topics
Who we are
Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.